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KMID : 0191120220370260206
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Journal of Korean Medical Science
2022 Volume.37 No. 26 p.206 ~ p.206
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The Association Between Bacille Calmette-Guerin Vaccination and Nontuberculous Mycobacterial Pulmonary Disease
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Kwak Nak-Won
Hwang Ha-Won
Kim Hyung-Jun
Lee Hyun-Woo
Yim Jae-Joon
Lee Chang-Hoon
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Abstract
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This study aimed to investigate the association between Bacille Calmette-Guerin (BCG) vaccination and nontuberculous mycobacterial pulmonary disease (NTM-PD). Patients in the prospective NTM-PD cohort were matched to healthy controls to measure the association between BCG and NTM-PD development. The clinical course of NTM-PD patients was also evaluated to investigate the association between BCG and NTM-PD progression. BCG scars were not associated with NTM-PD development (adjusted odds ratio [OR], 2.04; 95% confidence interval [CI], 0.96?4.34) or progression (adjusted OR, 1.61; 95% CI, 0.92?2.81). In conclusion, BCG vaccination was not associated with the development or progression of NTM-PD.
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KEYWORD
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Bacille Calmette-Guerin, Vaccination, Nontuberculous Mycobacteria
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